Alkaline Water Research and Health Benefits
1) Antioxidant and Prevents Brain Damage
Unlike other antioxidants, H2 has the unique capability of crossing cell membranes and targeting organelles such as the mitochondria and nucleus [R].
Drinking hydrogen water prevented the development of Parkinson’s disease in an experiment on rats. Hydrogen water reduced oxidative stress and prevented cognitive impairment associated with dementia and Parkinson’s disease [R].
Hydrogen water prevented both the development and progression of neural degeneration, and suppressed neuronal loss in another Parkinson’s disease mice study [R].
Additionally, in a study on patients with Parkinson’s disease, it was found that the intake of hydrogen water reduces neurotoxic damage, which agrees with previous studies on animals. There were also no adverse effects from the hydrogen water at high doses (1000 mL/day) [R].
2) May Improve Mood Disorders
Hydrogen water restored the natural growth of brain cells in mice. Because antidepressants increase adult neurogenesis, hydrogen water may be used for improving depression and some mental disorders [R,R2].
3) Suppresses Inflammation
In a study, patients with rheumatoid arthritis, a chronic inflammatory disease, drank .5 L/day of hydrogen water for 4 weeks. By the end of the study all patients with early rheumatoid arthritis achieved remission and 20% became symptom-free [R,R2].
4) Reduces Muscle Fatigue, Motor Deficits, and Muscle Degeneration
In a study on mice with Duchenne muscular dystrophy (DMD), a devastating muscle disease, hydrogen water prevented abnormal body mass gain and increased the production of the antioxidant glutathione peroxidase. It was found that hydrogen water can potentially improve muscular dystrophy in DMD patients [R].
5) Prevents Metabolic Syndrome
Hydrogen water significantly reduced fatty liver in mice with type 2 diabetes and obesity as well as in mice with a high–fat-diet-induced fatty liver. Also, levels of glucose, insulin, and triglycerides were decreased by stimulating energy metabolism [R].
A study in rats showed that hydrogen water could prevent atherosclerosis (hardening of the arteries) [R].
In a study on patients with the potential for metabolic syndrome, drinking hydrogen water (1.5 – 2 L/day) for 8 weeks showed an increase in HDL-cholesterol (“good” cholesterol) and a decrease in total cholesterol [R].
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6) May Help in Weight Loss
Long-term drinking of hydrogen water controlled body fat and weight in rats, despite no change in food and water intake [R].
7) Enhances Mitochondrial Function
Clinical studies have shown that drinking hydrogen water directly protects the mitochondria and improves the outcome of mitochondrial disorders [R].
Drinking hydrogen water also stimulates energy metabolism (as measured by oxygen consumption and CO2 production) [R].
8) Treats Diabetes
A clinical trial in patients with type 2 diabetes and impaired glucose tolerance showed that drinking hydrogen water (900 mL) for 8 weeks decreased cholesterol, normalized glucose tolerance and improved insulin resistance in most of the treated patients [R].
9) May Treat Metabolic Acidosis
Metabolic acidosis is a condition characterized by an increase in blood acidity, which can be exacerbated with exercise. A study in healthy physically active males found that a daily intake of hydrogen-rich water for 14 days increased the pH of the blood before and after exercise with no side effects. The study concluded that drinking hydrogen water is safe and may have an alkalizing effect in the blood [R].
10) May Prevent Cancer
Heated hydrogen water was found to be an effective anti-tumor agent [R].
In human tongue and connective tissue cancer cells, hydrogen water suppressed tumor colony growth by reducing oxidative stress [R].
Hydrogen water also inhibited angiogenesis (blood vessel growth) in cultured human lung cancer cells [R].
11) Reduces Side Effects of Cancer Treatments
In a study on patients receiving radiation therapy for malignant liver tumors, drinking hydrogen water (1.5 – 2 L/day) suppressed oxidative stress (as measured by elevation of total hydroperoxide levels) and prevented the loss of appetite [R].
12) Boosts Skin Health
Hydrogen water administered intravenously (into the vein) to patients with acute erythematous skin diseases caused the erythema (redness) and associated symptoms to significantly improve [R].
Bathing in hydrogen water for 3 months significantly improved wrinkles in the skin in a human study [R].
Hydrogen water also reduced human skin cell damage from ultraviolet (UV) rays [R].
13) Enhances Wound Healing
Hydrogen water intake via tube feeding in elderly patients reduced the wound size of pressure ulcers and enhanced recovery [R].
14) Limits Damage of Transplant Organs
Hydrogen water in the form of a preservation solution reduced the damage of a variety of organs during transplantation [R].
15) Improves Bladder Dysfunctions
In a study on rats that were surgically induced with a bladder obstruction, drinking hydrogen water significantly suppressed bladder weight increase and oxidative stress. Also, hydrogen water reversed the decreased responses to muscles and electric field stimulation. These results suggest that hydrogen water could help patients with a bladder obstruction by decreasing oxidative stress [R].
Treating diabetic mice with hydrogen water significantly improved heart muscle function, indicating that molecular hydrogen could be useful for diabetic heart muscle disease [R].
17) Protects the Eye
H2-loaded eye drops facilitated the recovery process after retinal injury in rats [R].
Treating the cornea with hydrogen solution significantly reduced angiogenesis (blood vessel growth) after alkali-burn injury in mice, indicating that hydrogen therapy may prevent blindness caused by chemical burns of the eye [R].
18) Prevents Hearing Loss
Molecular hydrogen protects auditory hair cells from oxidative damage [R].
Studies in guinea pigs found that hydrogen-rich saline and water prevented the death of cochlear hair cells after noise exposure, indicating that hydrogen water may protect against noise-induced hearing loss [R,R2,R3].
19) Combats Allergy
Drinking hydrogen water eliminated an immediate-type allergic reaction in mice [R].
Atopic dermatitis (AD) is an allergic inflammatory skin disorder characterized by red, scaly rashes on the skin. In mice with AD-like skin, hydrogen water was able to improve symptoms by suppressing inflammation (through manipulation of Th1and Th2 responses) [R].
20) Ameliorates Kidney Disease
A study in rats found that hydrogen-rich water was able to improve kidney dysfunction from toxic damage by reducing oxidative stress and chemical waste products (creatinine (Cr) and blood urea nitrogen (BUN)) [R].
Drinking hydrogen water also reduced inflammation and blood pressure in hemodialysis patients [R].
21) Protects the Liver
Drinking hydrogen water suppressed liver fibrogenesis in mice by protecting liver cells from free-radical damage [R].
Hydrogen water also significantly improved liver function and reduced oxidative stress in patients with chronic hepatitis B [R].
22) Promotes Gut Health
Hydrogen-rich water alleviated stomach mucosal injury induced by aspirin in rats (by suppressing oxidative stress and inflammation), indicating that hydrogen water may protect healthy individuals from gut damage caused by oxidative stress [R,R2].
23) Protects the Lung
A study found that pre-treating mice with hydrogen water before irradiation exposure increased survival rates and protected the heart from radiation-induced damage [R].
Hydrogen treatment also inhibited irradiation-induced death in cultured human white blood cells, suggesting that hydrogen may be used as an effective radioprotective agent [R].
25) Relieves Pain
In mice, oral hydrogen water intake was found to alleviate common symptoms of neuropathic pain (allodynia and thermal hyperalgesia). The study concluded that hydrogen water may be helpful for relieving nerve pain in a clinical setting [R].
26) May Prolong Lifespan
H2 treatment delayed the replicative lifespan of bone marrow stem cells by reducing oxidative stress [R].
When human umbilical vein endothelial cells (HUVECs) were grown in a hydrogen-rich medium, both oxidative stress and cellular aging were suppressed. The study concluded that drinking hydrogen water may increase longevity in humans [R].
27) Antibacterial and May Promote Oral Health
A study found that hydrogen water may improve oral hygiene because of its antibacterial effect against cavity and gum disease-causing bacteria [R].
In patients with gum infection, drinking hydrogen-rich water improved disease symptoms and enhanced the effects of non-surgical gum disease treatment [R].